Consider the "Parody 2" effect in video game machinima. Red vs. Blue Season 1 was a clever use of Halo assets. Season 2 (Parody 2 of the original concept) introduced Church’s time travel, the confusing love triangle, and the legendary "Why are we here?" philosophical rant. Without Parody 2, the show would have been a footnote. With it, it became a 15-season empire.
By the time we reach Parody 2, the barrier is gone. The creator assumes you have already seen Parody 1. They assume you are fluent in the meta-language. Consequently, Parody 2 is free to invent. It no longer needs to hit the "greatest hits" of the source material. Instead, it creates its own mythology.
Ooh, ooh, nothing matters, nothing matters to me Mama, oooh (sock, you're so free) Nothing matters, nothing matters to me Mama, oooh (sock, you're just a sock to me)
Look at Weird Al Yankovic’s career. "Eat It" (Parody 2 of "Beat It") was huge. But "Amish Paradise" (Parody 2 of "Gangsta's Paradise") is arguably his most iconic track. He moved from mimicking Michael Jackson’s choreography to creating an entire alternate universe of horse-and-buggy rap. He didn't just change the lyrics. He changed the ethos .