Historically, the University of Texas Medical Branch (UTMB) has been progressive in distributing this knowledge. For a significant period, electronic versions of earlier editions were made freely available through the NCBI (National Center for Biotechnology Information) Bookshelf. This open-access approach was ahead of its time and contributed heavily to the book's "cult classic" status online.

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Chapters include learning objectives , summary boxes , and review questions to reinforce key concepts.