Before trying complex fixes, verify which version of the game you own:
For some users, the game fails to find necessary PhysX files in its own directory. batman arkham asylum general protection fault fix
If the GPF occurs right as you try to start a game from the main menu, your save file might be the culprit. Before trying complex fixes, verify which version of
: Reinstalling PhysX is a common fix. Run the installer found in the redist folder or download the NVIDIA PhysX Legacy Driver . Before trying complex fixes
"I am vengeance. I am the night. I am... the patch that finally makes Unreal Engine 3 stop crashing." – Batman (Probably)
: In the same menu, set the game to run in compatibility mode for Windows 7 or Windows 8 .